?-1-Melanocyte Stimulating Hormone (MSH), amide

Category : Melanocyte Stimulating Hormones and Analogs

Purity : 95%

Sequence (One Letter Code) : YVMGHFRWDRF-NH2

Sequence (Three letter Code) : {TYR}{VAL}{MET}{GLY}{HIS}{PHE}{ARG}{TRP}{ASP}{ARG}{PHE}-NH2

Gamma-MSH (Melanocyte Stimulating Hormone), a putative hormone in the N-terminal region of the ACTH/beta- endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3-MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v. Gamma-MSH peptides have low intrinsic melanotropic activity in mammalian melanoma cells; the specific pigmentary responses appear to be affected by the structure of the C-terminal portion.

Mol Wt : 1512.9