Mouse Phospho-ABL-1 (Y276) mAb

Specificity: Mouse phospho-ABL1 (Y276)

Source: Rabbit

IgG Type: rabbit IgG

Background: Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired.

Other Name: Abelson murine leukemia viral oncogene homolog 1