Mouse Phospho-Caspase-6 (S257) mAb
Specificity: Mouse phospho-Caspase 6 (S257) Size: 0.1 mg
IgG Type: rabbit IgG
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins.
Overexpression promotes programmed cell death. Activation is suppressed by phosphorylation at Ser-257. Heterodimer of a 18 kDa (p18) and a 11 kDa (p11) subunit.
Other Name: Apoptotic protease Mch-2
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