TAT

Ontores Biotechnologies

Category : Virus Peptide

Purity : 95%

Sequence (One Letter Code) : YGRKKRRQRRR-NH2

Sequence (Three letter Code) : {TYR}{GLY}{ARG}{LYS}{LYS}{ARG}{ARG}{GLN}{ARG}{ARG}{ARG}-NH2

TaT is a transcriptional transactivator protein that binds to a regulatory element in the HIV-1 long terminal repeat. By recruiting P-TEFb to TAR, TaT promotes transcription of viral mRNA. This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis. TaT has similar immunosuppressive effects as transforming growth factor-beta (TGF beta) and both inhibit lymphocyte proliferation.

Mol Wt : 1558.85

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0.5 mg

£167.70 / €234.78 ONP10880

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