Category : Virus Peptide
Purity : 95%
Sequence (One Letter Code) : YGRKKRRQRRR-NH2
Sequence (Three letter Code) : {TYR}{GLY}{ARG}{LYS}{LYS}{ARG}{ARG}{GLN}{ARG}{ARG}{ARG}-NH2
TaT is a transcriptional transactivator protein that binds to a regulatory element in the HIV-1 long terminal repeat. By recruiting P-TEFb to TAR, TaT promotes transcription of viral mRNA. This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis. TaT has similar immunosuppressive effects as transforming growth factor-beta (TGF beta) and both inhibit lymphocyte proliferation.
Mol Wt : 1558.85
Shipping | Standard |
---|
Buy now
All prices shown are exclusive of VAT