Angiotensin 1/2 (1-8) amide

Short Summary : Vasoconstrictor

Category : Cardiovascular

Purity : 0.9893

CAS Number :

Formula : C50H72N14O11

Molecular Weight : 1045.19

SMILE : OC(C[C@H](N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@@H]([C@H](CC)C)C(N[C@H](C(N2[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N)=O)=O)CCC2)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)=O

Solubility : Soluble in DMSO

Storage : Store at -20°C

Description : The physiologically active peptide angiotensin-2 (angiotensin 1- 8) is yielded from angiotensin-1, a substrate of ACE (angiotensin converting enzyme), by removing a dipeptide.
Angiotensin 1/2 (1-8) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide) is a peptide analogue to angiotensin II that is used as a vasopressor agent in the treatment of certain types of shock and circulatory collapse. It is a potent vasoconstrictor and is used as a cardiac stimulant.
Fig 1. Formula of angiotensin (1-8).

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