Floxuridine

Short Summary : Antineoplastic antimetabolite

Category : DNA Damage/DNA Repair|DNA Synthesis

Purity : 0.98

CAS Number : 50-91-9

Formula : C9H11FN2O5

Molecular Weight : 246.19

SMILE : C1C(C(OC1N2C=C(C(=O)NC2=O)F)CO)O

Solubility : >12.3mg/mL in DMSO

Storage : Store at -20°C

Description : Antineoplastic antimetabolite. Exhibits antiproliferative activity; inhibits thymidylate synthetase and disrupts DNA replication in human cells. Induces double-strand DNA breaks; activates ATR and ATM signaling pathways. Induces phosphorylation of Chk1 an

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