Anamorelin

Short Summary : Ghrelin receptor agonist, synthetic, orally active

Category : GPCR/G protein|GHSR

Purity : 0.98

CAS Number : 249921-19-5

Formula : C31H42N6O3

Molecular Weight : 546.7

SMILE : CC(C)(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)N3CCCC(C3)(CC4=CC=CC=C4)C(=O)N(C)N(C)C)N

Solubility : Soluble in DMSO

Storage : Store at -20°C

Description : Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite.

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