Anamorelin hydrochloride

Short Summary : GHSR/ghrelin receptor agonist

Category : GPCR/G protein|GHSR

Purity : 0.98

CAS Number : 861998-00-7

Formula : C31H43ClN6O3

Molecular Weight : 583.16

SMILE : CC(/C(O)=N/[C@](C(N1CCC[C@@](C1)(C(N(N(C)C)C)=O)CC2=CC=CC=C2)=O)([H])CC3=CNC4=CC=CC=C34)(N)C.Cl

Solubility : DMSO

Storage : Store at -20°C

Description : Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite.

Download datasheet