Avermectin B1b

Short Summary : mixture of avermectins

Category : Microbiology & Virology|Antibiotic

Purity : 0.98

CAS Number : 65195-56-4

Formula : C47H70O14

Molecular Weight : 859.05

SMILE : CC([C@](O1)([H])[C@@](C=C[C@@]21C[C@](O3)([H])C[C@@](O2)([H])C/C([H])=C([C@](O[C@@]4([H])C[C@@](OC)([H])[C@](O[C@@]5([H])C[C@@](OC)([H])[C@](O)([H])[C@](O5)([H])C)([H])[C@](O4)([H])C)([H])[C@@](/C([H])=C([H])/C([H])=C([C@@]67O)CO[C@]7([H])[C@@](O)([H])C(

Solubility : DMSO

Storage : Store at -20°C

Description : Avermectin B1 is a mixture of avermectins containing >80% avermectin B1a and
In vitro: The avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium. Avermectin B1 is a natural fermentation product of this bacterium.
In vivo: Avermectin B1 therapy resulted in significant decreases in mean strongyle egg after treatment. All horses given ivermectin or avermectin B1 had zero strongyle egg counts 14 and 28 d after treatment. The oral administration of avermectin B1 appeared to be highly efficacious against intestinal strongyles and Onchocera microfilaria [1].
Clinical trial: Currently no clinical data are available
Reference:[1] Mogg TD, Pollitt CC, Willmore JP, Thompson H. Efficacy of avermectin B1 given orally against equine intestinal strongyles and Onchocera microfilaria. Aust Vet J. 1990;67(11):399-401.

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