Azathramycin

Short Summary : Macrolide antibiotic

Category : Microbiology & Virology|Antibiotic

Purity : 0.98

CAS Number : 76801-85-9

Formula : C37H70N2O12

Molecular Weight : 734.96

SMILE : CC[C@](O1)([H])[C@]([C@@](O)([H])[C@@](NC[C@](C[C@]([C@@](O[C@@]2([H])[C@@](O)([H])[C@](N(C)C)([H])C[C@@](O2)([H])C)([H])[C@@]([C@@](O[C@@]3([H])C[C@]([C@](O)([H])[C@](O3)([H])C)(OC)C)([H])[C@@](C1=O)([H])C)([H])C)(O)C)([H])C)([H])C)(O)C

Solubility : 25℃: DMSO

Storage : Store at -20°C

Description : Description:
IC50 Value: N/A
Azithromycin (Zithromax, Azithrocin, Zmax, Azin, Zedd) is an azalide, a subclass of macrolide antibiotics. Azithromycin is one of the world’s best-selling antibiotics.
in vitro: The geometric mean 50% inhibitory concentration (IC50) of azithromycin was 2,570.3 (95% CI=2,175.58 to 3,036.58) ng/ml [1]. Azithromycin, clarithromycin and roxithromycin inhibited the proliferation of both the concanavalin A- and superantigen-stimulated PBMCs dose-dependently. The effect of azithromycin was the strongest, with IC50 values of less than 5 g/ml [2].
in vivo: Azithromycin produced a slightly higher percentage of patients with a greater than 80% reduction in their inflammatory acne lesions (85.7%) vs. an average of 77.1% for all other agents [3].
Clinical trial: N/A

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