Benfotiamine

Short Summary : Drug for painful nerve condition

Category : Others|Others

Purity : 0.985

CAS Number : 22457-89-2

Formula : C19H23N4O6PS

Molecular Weight : 466.45

SMILE : CC1=NC=C(C(=N1)N)CN(C=O)C(=C(CCOP(=O)(O)O)SC(=O)C2=CC=CC=C2)C

Solubility : <4.66mg/mL in DMSO

Storage : Store at -20°C

Description : Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways(the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG) protein kinase C (PKC) pathwayof hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1.

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