CID-2858522

Short Summary : NF-κB pathway inhibitor

Category : Immunology/Inflammation|IκB/IKK

Purity : 0.98

CAS Number : 758679-97-9

Formula : C28H39N3O3

Molecular Weight : 465.63

SMILE : CC1=CC2=C(N(CC(C3=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C3)=O)C(NCCCO)=N2)C=C1C

Solubility : Soluble in DMSO > 10 mM

Storage : Store at -20°C

Description : CID-2858522, a 2-aminobenzimidazole compound, selectively inhibits the NF-κB pathway (IC50 < 0.1 μM for PMA-stimulated IL-8 production) induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways.

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