CYT387 sulfate salt

Short Summary : JAK1/JAK2 inhibitor

Category : Chromatin/Epigenetics|JAK

Purity : 0.98

CAS Number : 1056636-06-6

Formula : C23H26N6O10S2

Molecular Weight : 610.62

SMILE : C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N.OS(=O)(=O)O.OS(=O)(=O)O

Solubility : Soluble in DMSO

Storage : Store at -20°C

Description : CYT387 is an ATP-competitive small molecule JAK1/JAK2 inhibitor with IC50 of 11 and 18 nM for JAK1 and JAK2, respectively. CYT387 is useful for treatment of myeloproliferative disorders and anti-cancer.

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