LY450108

Short Summary : AMPA receptor potentiator

Category : Membrane Transporter/Ion Channel|AMPAR

Purity : 0.98

CAS Number : 376594-67-1

Formula : C19H22F2N2O3S

Molecular Weight : 396.45

SMILE : CC(S(=O)(NCC(C1=CC=C(NC(C2=CC(F)=CC(F)=C2)=O)C=C1)C)=O)C

Solubility : DMSO

Storage : Store at -20°C

Description : LY450108 is an alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor potentiator. AMPA receptors mediate most of the excitatory neurotransmission and play a key role in synaptic plasticity in the mammalian central nervous system (CNS). Recent evidence has shown that in addition to modulating fast synaptic plasticity and memory processes, AMPA receptor potentiators alter downstream signalling pathways and may thereby have utility in other CNS disorders.

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