Maropitant

Short Summary : NK1 receptor antagonist

Category : Neuroscience|Substance P/NK1 Receptor

Purity : 0.98

CAS Number : 147116-67-4

Formula : C32H40N2O

Molecular Weight : 468.67

SMILE : CC(C)(C1=CC(CNC2C3CCN(CC3)C2C(C4=CC=CC=C4)C5=CC=CC=C5)=C(OC)C=C1)C

Solubility : DMSO

Storage : Store at -20°C

Description : Maropitant is a neurokinin (NK1) receptor antagonist. Maropitant is the first NK1 receptor antagonist developed to treat and prevent emesis in dogs. Treatment with 1 mg/kg Maropitant citrate, significantly reduced the size of ulcerative dermatitis (UD) lesions in mice. Intravenous Maropitant decreased (p 0.05) the MAC (2.17 ± 0.34% and 1.92 ± 0.12%, respectively).

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