Medetomidine

Short Summary : α2-adrenoceptor agonist

Category : GPCR/G protein|Adrenergic Receptor

Purity : 0.98

CAS Number : 86347-14-0

Formula : C13H16N2

Molecular Weight : 200.28

SMILE : CC1=C(C)C(C(C2=CN=CN2)C)=CC=C1

Solubility : DMSO

Storage : Store at -20°C

Description : Medetomidine is a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). Medetomidine displays greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). Medetomidine inhibits twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0). Active in vivo; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects.

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