Mibefradil dihydrochloride

Short Summary : Ca2+ channel blocker ,antihypertensive

Category : Membrane Transporter/Ion Channel|Calcium Channel

Purity : 0.98

CAS Number : 116666-63-8

Formula : C29H40Cl2FN3O3

Molecular Weight : 568.55

SMILE : CC(C)C1C2=C(CCC1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)COC)C=C(C=C2)F.Cl.Cl

Solubility : Soluble in DMSO > 10 mM

Storage : Store at -20°C

Description : Mibefradil is calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50 values of 2.7 μM and 18.6 μM for T-type and L-type channels respectively. Mibefradil is antihypertensive agent for the treatment of hypertension and chronic angina pectoris.

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