MK-2894 sodium salt

Short Summary : EP4 antagonist

Category : GPCR/G protein|EP4 Receptor

Purity : 0.98

CAS Number : 1006036-88-9

Formula : C25H21F3NNaO3S

Molecular Weight : 495.49

SMILE : CC1=C(CC2=CC=C(C(F)(F)F)C=C2)C(C(NC3(C4=CC=C(C([O-])=O)C=C4)CC3)=O)=C(C)S1.[Na+]

Solubility : DMSO

Storage : Store at -20°C

Description : MK-2894, a highly potent and selective second generation EP4 antagonist.MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.

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