NB-598

Short Summary : SE inhibitor

Category : Others|Squalene epoxidase

Purity : 0.98

CAS Number : 131060-14-5

Formula : C27H31NOS2

Molecular Weight : 449.67

SMILE : CCN(CC1=CC(OCC2=CC(C3=CSC=C3)=CS2)=CC=C1)C/C=C/C#CC(C)(C)C

Solubility : DMSO

Storage : Store at -20°C

Description : NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598.

Download datasheet