NB-598 Maleate

Short Summary : Squalene epoxidase inhibitor

Category : Others|Squalene epoxidase

Purity : 0.98

CAS Number : 155294-62-5

Formula : C31H35NO5S2

Molecular Weight : 565.74

SMILE : CCN(CC=CC#CC(C)(C)C)CC1=CC(=CC=C1)OCC2=CC(=CS2)C3=CSC=C3.C(=CC(=O)O)C(=O)O

Solubility : >16.5mg/mL in DMSO

Storage : Store at -20°C

Description : NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598.

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