NB-598 Maleate salt

Short Summary : SE inhibitor

Category : Others|Squalene epoxidase

Purity : 0.98

CAS Number : 136719-26-1

Formula : C31H35NO5S2

Molecular Weight : 565.74

SMILE : CCN(CC1=CC(OCC2=CC(C3=CSC=C3)=CS2)=CC=C1)C/C=C/C#CC(C)(C)C.O=C(O)/C=C/C(O)=O

Solubility : DMSO

Storage : Store at -20°C

Description : NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598.

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