Phenformin HCl

Short Summary : biguanidine drug with anti-diabetic activity

Category : Others|Others

Purity : 0.98

CAS Number : 834-28-6

Formula : C10H16ClN5

Molecular Weight :

Molecular Weight : 241.72

SMILE : C1=CC=C(C=C1)CCN=C(N)N=C(N)N.Cl

Solubility : >12.1mg/mL in DMSO

Storage : Store at -20°C

Description : Phenformin HCl is a hydrochloride salt of the biguanidine drug phenformin.Phenformin is the biguanide class that displays anti-diabetic activity.In 5 patients with diabetes mellitus, phenformin reduced the blood glucose values and glycosuria. In 4 of 5 patients, cholesterol and total lipid levels were dropped. Also, Phenformin had no impact on glucose, nor the insulin levels after intravenous glucose loading.References:[1]. Geldermans CA, Terpstra J, Krans HM. The effect of phenformin-HCl on patients with diabetes mellitus, studied under strict balance conditions. Diabetologia, 1975, 11(5): 475-482.

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