Kaempferol

Short Summary : Apoptosis inducer;antioxidant;flavonoid

Category : Apoptosis|Apoptosis Inducers

Purity : 0.98

CAS Number : 520-18-3

Formula : C15H10O6

Molecular Weight :

Molecular Weight : 286.24

SMILE : C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O

Solubility : >12.3mg/mL in DMSO

Storage : Store at -20°C

Description : Naturally occurring flavonoid found in Gingko biloba and red wines that activates the mitochondrial Ca2+ uniporter (EC50 = 7 M). Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro.

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