AMI-1

Short Summary : PRMT1 inhibitor

Category : Chromatin/Epigenetics|Histone Methyltransferase

Purity : 0.98

CAS Number :

Formula : C21H12N2O9S2Na4

Molecular Weight : 592.42

SMILE : C1=CC2=C(C=C(C=C2C=C1NC(=O)NC3=CC4=CC(=CC(=C4C=C3)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])[O-].[Na+].[Na+].[Na+].[Na+]

Solubility : Soluble in DMSO

Storage : Store at -20°C

Description : Potent, cell permeable and specific protein arginine N-methyltransferase 1 (PRMT1) inhibitor (IC50 = 8, 8 M), Does not compete for the AdoMet (S-adenosyl-L-methionine, SAM) binding site, Blocks peptide substrate binding, HIV-1 RT polymerase inhibitor (IC50 = 5, 0 M).

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