Arctigenin

Short Summary : Anti-inflammatory, antiproliferative

Category : MAPK Signaling|MEK1/2

Purity : 0.98

CAS Number : 7770-78-7

Formula : C21H24O6

Molecular Weight :

Molecular Weight : 372.41

SMILE : COC1=C(C=C(C=C1)CC2COC(=O)C2CC3=CC(=C(C=C3)O)OC)OC

Solubility : >17.2mg/mL in DMSO

Storage : Desiccate at -20°C

Description : Antioxidant, anti-inflammatory, antiproliferative and antiviral agent. Inhibits LPS-induced iNOS expression via inhibition of IB phosphorylation and p65 nuclear translocation (IC50 = 10 nM). Inhibits HIV-1 replication in vitro. Also potently inhibits MKK1 (MEK1) (IC50 = 0.5 nM) and provides neuroprotection by binding to kainate receptors.

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