Auranofin
Product Description : Auranofin is a proteasomal deubiquitinase inhibitor with inhibition of the proteasome-associated deubiquitinases (DUBs) UCHL5 and USP14 rather than 20S proteasome, which is required for Auranofin-induced cytotoxicity. It selectively inhibits tumor growth in vivo and induces cytotoxicity in cancer cells from acute myeloid leukemia patients and by blocking NF-?B activation, Auranofin can attenuats the cardiac hypertrophy.
CAS Number : 34031-32-8
Molecular Weight : 679.49
Format : C20H35AuO9PS
Purity : ?98%
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