Beta-Lipotropin (1-10), porcine

Short Summary : Morphine-like substance

Category : Neuroscience|Neuroscience Peptides

Purity : 0.9999

CAS Number : 77875-68-4

Formula : C42H66N10O15

Molecular Weight : 951.03

SMILE : N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(NCC(N[C@@H](C)C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(N[C@@H](CCC(O)=O)C(N3[C@@H](CCC3)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Solubility : >95.1mg/mL in DMSO

Storage : Store at -20°C

Description : Morphine-like substances exist in brain or the pituitary of various species. Beta-lipotropin (beta-LPH) was found to contain within its C-terminal sequence the primary structure of these peptides.
Identity between the sequence of isolated fragments and thecarboxy terminal portion of the corresponding beta-lipotropins hasalso been observed in human and in porcine pituitary and hypothalamic-neurohypophysis extracts.
Reference:
1. Bradbury, A.F., Smyth, D.G. and Snell, C.R. (1976), Biochem. Biophys. Res. Commun. 6!J, 950-956.
2. Ling, N., Burgus, R. and Guillemin, R. (1976). Proc. Natl. Acad. Sci. USA., 73, 3942-3946.

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