CCT 137690

A potent, orally bioavailable Aurora kinases inhibitor with IC50 of 15/25/19 nM for Aurora A/B/C; displays antiproliferative activity in a range of human tumor cell lines, including SW620 colon carcinoma (GI50=0.30 uM) and A2780 ovarian cancer cell line (GI50=0.14 uM); exhibits in vivo efficacy with no observed toxicities in SW620 colon carcinoma xenografts.

Target : Aurora Kinase

CAS Number : 1095382-05-0

Formula Weight : 551.4813

Molecular Formula : C26H31BrN8O

Purity : >98% (HPLC)

Storage : (-20?)

Shipping Conditions : With Ice Pack

Stability : ? 2 years

Research use only, not for human use.