CHAPS

Short Summary : Zwitterionic detergent for membrane proteins,nondenaturing

Category : DNA Damage/DNA Repair|HDAC

Purity : 0.98

CAS Number : 75621-03-3

Formula : C32H58N2O7S

Molecular Weight : 614.88

SMILE : CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C

Solubility : Soluble in water

Storage : Store at -20°C

Description : CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins. CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons. CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions and is electrically neutral. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. The critical micelle concentration of CHAPS is 6-10mM.

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