Cobimetinib (R-enantiomer)

Short Summary : Selective MEK inhibitor

Category : MAPK Signaling|MEK1/2

Purity : 0.98

CAS Number : 934660-94-3

Formula : C21H21F3IN3O2

Molecular Weight : 531.31

SMILE : C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O

Solubility : Soluble in DMSO

Storage : Store at -20°C

Description : GDC-0973(XL-518) is a selective inhibitor of MEK. GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors.

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