Dexrazoxane HCl (ICRF-187, ADR-529)

Short Summary : Topoisomerase II inhibitor,intracellular ion chelator,cardioprotective agent

Category : DNA Damage/DNA Repair|Topoisomerase

Purity : 0.9976

CAS Number : 149003-01-0

Formula : C11H16N4O4.HCl

Molecular Weight : 304.73

SMILE : CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl

Solubility : >15.2mg/mL in DMSO

Storage : Store at -20°C

Description : Dexrazoxane hydrochloride is a cardioprotective agent. As a derivative of EDTA, dexrazoxane chelates iron, but the precise mechanism by which it protects the heart is not known. This agent is used to protect the heart against the cardiotoxic side effects

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