IDO inhibitor 1

Short Summary : Indoleamine-2,3-dioxygenase inhibitor

Category : Metabolism|IDO

Purity : 0.9983

CAS Number : 1204669-37-3

Formula : C11H13BrFN7O4S

Molecular Weight : 438.23

SMILE : BrC1=CC(/N=C(NO)C2=NON=C2NCCNS(=O)(N)=O)=CC=C1F

Solubility : >19.35mg/mL in DMSO

Storage : Store at -20°C

Description : IDO inhibitor 1 is a potent and novel indoleamine-2,3 dioxygenase (IDO) inhibitor with IC50 value IDO is an enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine and permits tumor cells to escape the immune system. Reference:[1]. Andrew P. Combs, et al. 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase. Patent Numeber: EP 2315756 A2http://www. google.com/patents/EP2315756A2 cl=en

Download datasheet