NG25

Short Summary : TAK1 inhibitor

Category : TGF-? / Smad Signaling|TAK1

Purity : 0.98

CAS Number : 1315355-93-1

Formula : C29H30F3N5O2

Molecular Weight : 537.58

SMILE : CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F

Solubility : Soluble in DMSO

Storage : Store at -20°C

Description : NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells.

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