NPS-2143 hydrochloride

Short Summary : Calcium ion-sensing receptor antagonist

Category : GPCR/G protein|CaSR

Purity : 0.9994

CAS Number : 324523-20-8

Formula : C24H26Cl2N2O2

Molecular Weight : 445.38

SMILE : CC(C)(CC1=CC2=CC=CC=C2C=C1)NCC(COC3=C(C(=CC=C3)Cl)C#N)O.Cl

Solubility : Soluble in DMSO > 10 mM

Storage : Store at -20°C

Description : NPS-2143 is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively.NPS-2143 is useful for treatment of osteoporosis;

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