NSC 377071

NSC 377071 (NSC-377071, NSC377071, Cambendazole) is a novel ATG4B antagonist that inhibits autophagy, with no effect on mTOR and PI3K activities; directly inhibits cellular ATG4B activity induced by starvation or rapamycin and suppresses the lipidation of LC3B and autophagosome formation in response to starvation, suppresses Saos-2 osteosarcoma growth in vivo.

Target : Atg

CAS Number : 26097-80-3

Formula Weight : 302.352

Molecular Formula : C14H14N4O2S

Purity : >98% (HPLC)

Storage : (-20?)

Shipping Conditions : With Ice Pack

Stability : ? 2 years

Research use only, not for human use.