NVP-BAG956

Short Summary : PI3K and PDK1 inhibitor

Category : PI3K/Akt/mTOR Signaling|PDK-1

Purity : 0.98

CAS Number : 853910-02-8

Formula : C28H21N5

Molecular Weight : 427.5

SMILE : CC1=NC2=CN=C3C=CC(C#CC4=CN=CC=C4)=CC3=C2N1C5=CC=C(C(C)(C#N)C)C=C5

Solubility : Soluble in DMSO > 10 mM

Storage : Store at -20°C

Description : NVP-BAG956(BAG 956) is a potent, ATP-competitive and selective dual PI3K and PDK1 inhibitor in vitro and in vivo,with IC50 values to be 56, 444, 34, 117 and 240 nM for PI3K p110 alpha, beta, delta and gamma and PDK1 kinases, respectively.

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