Riociguat

Short Summary : Soluble guanylate cyclase (sGC) stimulator

Category : Others|Guanylate Cyclase

Purity : 0.9992

CAS Number : 625115-55-1

Formula : C20H19FN8O2

Molecular Weight : 422.42

SMILE : CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC

Solubility : >17mg/mL in DMSO

Storage : Store at -20°C

Description : Riociguat (BAY 63-2521; BAY 632521) is a novel drug that is currently in clinical development by Bayer. Riociguat (BAY 63-2521; BAY 632521) is a stimulator of soluble guanylate cyclase (sGC). At the moment Phase III clinical trials investigate the use of riociguat as a new approach to treat two forms of pulmonary hypertension (PH): chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH). Riociguat constitutes the first drug of a novel class of sGC stimulators.

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