Ruxolitinib phosphate

Short Summary : JAK1/JAK2 inhibitor

Category : Chromatin/Epigenetics|JAK

Purity : 0.9973

CAS Number : 1092939-17-7

Formula : C17H21N6O4P

Molecular Weight : 404.36

SMILE : [HH].C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OOP(=O)=O

Solubility : >20.2mg/mL in DMSO

Storage : Store at -20°C

Description : INCB018424 (Ruxolitinib) is an orally bioavailable JAK inhibitor .(IC50 values for JAK1, JAK2 and JAK3 are 3, 5 and 332 nM, respectively).INCB018424 is useful for rheumatoid arthritis.

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