Safinamide

Short Summary : MAO-B inhibitor

Category : Membrane Transporter/Ion Channel|Calcium Channel

Purity : 0.98

CAS Number : 133865-89-1

Formula : C17H19FN2O2

Molecular Weight : 302.34

SMILE : CC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F

Solubility : Soluble in DMSO

Storage : Store at -20°C

Description : Safinamide (EMD 1195686; FCE 26743; ) is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, Safinamide (EMD 1195686; FCE 26743; ) is voltage-dependent sodium and calcium channel blocker. Safinamide (EMD 1195686; FCE 26743; ) appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals.

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