UNC 926 hydrochloride

Short Summary : Inhibitor of methyl lysine reader domain

Category : Chromatin/Epigenetics|MBT Domains

Purity : 0.98

CAS Number : 1184136-10-4

Formula : C16H21BrN2O.HCl

Molecular Weight : 373.72

SMILE : O=C(C1=CC=CC(Br)=C1)N2CCC(N3CCCC3)CC2.Cl

Solubility : Soluble in DMSO > 10 mM

Storage : Desiccate at RT

Description : Methyl-lysine reader antagonist; binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 M). Selectively inhibits, in a dose-dependent manner, the interaction between L3MBTL13XMBT-H4K20me1 in a peptide pull down assay.

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