CX3CR1 Rabbit Polyclonal Antibody
Picture Shows: Immunohistochemical staining of human heart tissue using CX3CR1 antibody at 2 μg/ml.
Background : CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines (2).
Alternate Names : CX3CR1 (NT), V28
Source : CX3CR1 antibody was raised against a peptide corresponding to amino acids 2 to 21 of human CX3CR1. The sequence differs from those of mouse and rat CX3CR1 by four amino acids (3,4).
Purification : Affinity chromatography purified via peptide column
Clonality/Clone : This is a polyclonal antibody.
Host : CX3CR1 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen : Human CX3CR1 (N-Terminus) Peptide (Cat. No. 2093P)
Application : CX3CR1 antibody can be used for detection of CX3CR1 by Western blot at 1:500 to 1:2000 dilution. An approximately 50 kDa band can be detected.
Tested Application : E, WB, IHC, FACS
Buffer : Antibody is supplied in PBS containing 0.02% sodium azide.
Blocking Peptide : Cat. No. 2093P – CX3CR1 Peptide
Storage : CX3CR1 antibody can be stored at 4˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Positive Control : Cat. No. 1306 – Human Spleen Tissue Lysate
Species Reactivity : H, M, R
Protein GI Number : 4503171
Accession Number : NP_001328
Short Description : (NT) HIV & chemokine receptor
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