Human Phospho-Caspase6 (S257) mAb

Specificity: Human phospho-Caspase 6 (S257)

Source: Rabbit

IgG Type: rabbit IgG

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins.

Overexpression promotes programmed cell death. Activation is suppressed by phosphorylation at Ser-257. Heterodimer of a 18 kDa (p18) and a 11 kDa (p11) subunit.

Other Name: Apoptotic protease Mch-2