Mouse Phospho-JNK (T183/Y185) mAb

Specificity: Mouse phospho-JNK (T183/T185)

Source: Rabbit

IgG Type: rabbit IgG

Background: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.

Other Name: Stress-activated protein kinase JNK